CT 99021
252917-06-9
465.3
C22H18CI2N8
DMSO
-20°C
CHIR99021 is a potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM). Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells. Promotes replication and survival of pancreatic beta cells3. CHIR-99021 enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors. Cell permeable and active in vivo.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.