19022-51-6
386.6
C25H38O3
DMF, DMSO, Ethanol, Methanol
-20°C
Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C inhibits human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 entry into cells. Blockade of this binding was considered by scientists at Merck as a potential new mode of action for the treatment of HIV-1 infection.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
