4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5- (hydroxymethyl)oxolan2-yl]-5-methylpyrimidin-2-one
2140-61-6
257.25
C10H15N3O5
Water
-20°C
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It has been used in epigenetics research, especially in studies involving DNA methylation processes including genomic imprinting and the control of gene expression and differentiation.
The presence of 5-methylcytidine in tRNA and rRNA molecules of a wide variety of organisms was first observed more than 40 years ago. Recent studies in eukaryotes have shown that mRNA modifications such as RNA-editing (conversion of an adenosine base to inosine), N6-adenine methylation (m6A), and 5-methylcytidine can change the coding sequence, alter splicing patterns, or change RNA stability.
5-methylcytidine is a modification that occurs both on DNA and RNA. In eukaryotes, this DNA modification has been extensively studied over the past years, and has been found to play a crucial role in genomic imprinting, X-chromosome inactivation, and suppression of repetitive elements.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
