6-O-methyl-erythromycin; A-56268; Antibiotic A 56268; TE 031
81103-11-9
748.0
C38H69NO13
DMF, DMSO, Ethanol, Ethanol:PBS (pH 7.2) (1:1)
-20°C
Clarithromycin (6-methoxyerythromycin) is a macrolide antibiotic active against a broad range of Gram positive bacteria. Clarithromycin was designed to enhance acid stability and improve oral bioavailability compared with erythromycin which is highly unstable to acidic conditions, undergoing a series of internal ketalisations between the 9-keto moiety and alcohols at C6 and C11. Omura and colleagues found that protection of the labile 6-OH group by methylation provided a simple but elegant solution.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
