A-54556 Factor B; N-[(2E,4E,6E)-1-oxo-2,4,6-octatrien-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-N-methyl-L-alanyl-L-alanyl-L-proline, (6→2)-lactone
1629166-56-8
704.8
C37H48N6O8
DMF, DMSO, Ethanol, Methanol
-20°C
A-54556B is an unusual depsipeptide isolated from Streptomyces hawaiiensis as antibiotics by researchers at Eli Lilly in 1985, featuring a trienone side chain.
A-54556B is a potent antibacterial against Gram positive and Gram negative bacteria including MRSA. It is a member of the recently re-discovered acyldepsipeptide (ADEP) antibiotics that act by activating and disregulating Clp-family proteins. ADEPs are considered important leads in the development of new generations of antibiotics against resistant bacteria.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
