ADEP 1; A-54556 Factor A; (4R)-N-[(2E,4E,6E)-1-oxo-2,4,6-octatrien-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-N-methyl-L-alanyl-L-alanyl-4-methyl-L-proline, (6→2)-lactone
95398-45-1
718.9
C38H50N6O8
DMF, DMSO, Ethanol, Methanol
-20°C
A-54556A is an unusual depsipeptide isolated from Streptomyces hawaiiensis by researchers at Eli Lilly in 1985, featuring a trienone side chain.
A-54556A is potently active against Gram positive and Gram negative bacteria, including MRSA. It was the original lead structure of the recently re-discovered acyldepsipeptide (ADEP) antibiotics that act by activating and disregulating Clp-family proteins. ADEPs are considered important leads in the development of new generations of antibiotics against resistant bacteria.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
