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U-18666A, 10 MG

Price$ 125.00
  • SKU: U-3002-10MG
  • Pack Size: 10 MG
Quantity
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(3β)-3-[2-(Diethylamino)ethoxy]androst-5-en-17-one, hydrochloride

3039-71-2

424.1

C25H41NO2 • HCl

Water, DMSO

-20°C


U-18666A is a useful tool for inhibition of cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum. Inhibits cholesterol transport in a variety of cell types such as macrophages and sympathetic neurons. May be used to induce a Neimann-Pick disease type C (NPC) or NPC-like phenotype in a variety of cell types. Inhibits cholesterol biosynthesis at the level of oxido-squalene cyclase (OSC). Inhibits Deng virus entry and replication. Induction of cataracts is a common toxic feature of OSC inhibitors such as U-18666A.

 



Research or further manufacturing use only, not for food or drug use.

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