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Sivelestat, 25 MG

Home Inhibitors Additional Inhibitors Sivelestat, 25 MG
Price$ 250.00

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5 MG $ 75.00 25 MG $ 250.00
  • SKU: S-4004-25MG
  • Pack Size: 25 MG
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Description

N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine, sodium; ONO-5046

127373-66-4

456.4

C20H21N2O7S • Na

DMSO

Room Temperature


Sivelestat potent and selective leukocyte elastase inhibitor, IC50 = 44 nM. Displays no activity at a variety of other proteases. Inhibits NF-kB activation and LTB4-induced neutrophil migration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo.

 



Research or further manufacturing use only, not for food or drug use.

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