2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
331001-62-8
362.4
C21H22N4O2
DMF, DMSO, Ethanol
-20°C
Cell-permeable. Maintains the undifferentiated state of embrryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatases PP2A, it prevents -catenin from switching coactivator usage from CBP to p300. The increase in -cateinin/CBP mediated transcription at the expense ofcateinin/CBP mediated transcription helps to maintain the murine stem cell pluripotency.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.