Ro 09-1978; 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine
154361-50-9
359.4
C15H22FN3O6
DMF, DMSO, Ethanol
-20°C
Capecitabine is a pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which occurs mainly in the liver by carboxyl-esterase. The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue. Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
