L-694,599; Squalestatin S1
142561-96-4
690.7
C35H46O14
DMF, DMSO, Ethanol, Methanol
-20°C
Zaragozic Acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
