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Cytochalasin B, Helminthosporium dematioideum, 1 MG

Price$ 52.25
  • SKU: C-1027-1MG
  • Pack Size: 1 MG
Quantity
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Cytochalasin B, Helminthosporium dematioideum, 1 MG

NSC 107658; Phomin

14930-96-2

479.6

C29H37NO5

DMF, DMSO, Ethanol

-20°C


Cytochalasin B is a heterotricyclic compound that acts as a mycotoxin. Cytochalasin B inhibits cytokinesis during cell division by preventing microfilament formation. While preventing cytokinesis from occurring, this compound exerts no effect on the division of the nucleus.

Cytochalasin B also inhibits several processes within cells, including both the formation of actin filaments and the normal transport of glucose. Cytochalasin B acts as a microtubule inhibitor isolated from Helminthosporium dematioideum.
 

Owing to its ability to permeate cells and inhibit several aspects of their ordinary activity, cytochalasin B has been used widely in cytological research to investigate cellular processes. Along with the other cytochalasins, this compound has also been studied as a potential anticancer drug.

In both in vitro and in vivo studies, cytochalasins have been shown to damage cancerous cells to a greater extent than non-cancerous cells. Another line of investigation into cytochalasin B's in vivo effects has focused on its ability to restore elasticity to the skin cells of mice by impeding f-actin polymerization. Cytochalasin B also induces cellular DNA fragmentation.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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